Manufacturer: Janssen Cilag
Pharmaceutical name: Domperidone
Pack: 10 pills (10 mg)
Motilium contains the active component, Domperidone, which aids in restoring your stomach's natural rhythm and facilitates proper food movement through your stomach. It alleviates discomfort from fullness and bloating while also acting on the brain's vomiting center to ease nausea.
Motilium primarily functions by inhibiting dopamine receptors located in the upper digestive tract. This leads to the tightening of muscles at the stomach's entrance, relaxation of muscles at the stomach's exit, and enhanced contractions of the stomach muscles. These effects accelerate the food's journey from the stomach to the intestine, which helps to physically prevent vomiting and lessen feelings of sickness, bloating, and fullness. Additionally, it stops food from moving backward through the stomach, thus preventing reflux (the return of stomach contents into the esophagus).
Side Effects: Allergic reactions, stimulation or enhancement of milk production by increasing prolactin levels from the pituitary gland, such as rashes or hives, have been documented. There have also been reports of abdominal cramps. Side effects like Dystonic reactions (extrapyramidal symptoms) may occur. Motilium has been associated with reversible increased serum prolactin levels, which may result in galactorrhea and gynecomastia.